LDL, ApoB and Heart Attack Risk: What the Evidence Shows
Turmeric & Curcumin Supplements: What the Research Actually Shows
Lies and deception characterise the majority of turmeric and curcumin supplements on the market today. That's a strong claim — but the evidence backs it up. There are legitimate use-cases for curcu...
Heart Disease Prevention: Saturated Fat, LDL Cholesterol, and the Diet Evidence
Across the world, cardiovascular disease death rates have been falling dramatically [1]. Today, science offers tools that could virtually eliminate coronary heart disease as a cause of death. But ...
Antioxidants and Aging: What the Research Shows
For years, antioxidants were hailed as miracle compounds that could slow aging, improve heart health, and enhance physical performance. Then, almost as quickly as they rose to fame, they fell out o...
Peanut Allergy Prevention: The Early Introduction Evidence
Dr. Ruchi Gupta did everything right to protect her daughter from peanut allergies — and it backfired. Dr. Gupta was a young doctor researching food allergies. She knew the advice. At the time, in ...
The FDA-Approved Alzheimer's Blood Test: What It Can and Cannot Tell You
The results hit like a ton of bricks — and they have critical implications for the recently FDA-approved Alzheimer's blood test. Researchers were packed wall-to-wall at a conference in San Diego. T...
Testosterone, Castration, and Lifespan: What the Research Shows
A massive new study published in Nature found that castration increases lifespan across vertebrate species, including zoo mammals, rodents, and wild animals [1]. This aligns with historical human d...
2026 Dietary Guidelines: What the Science Actually Says
For years, the message has been to "eat real food." It sounds simple, but the real challenge is figuring out what that actually means—and how official guidelines define it. With the release of the ...
Evidence-Based Cancer Screening: Which Tests Actually Save Lives
When it comes to preventing cancer, early detection is everything. But with all the noise online—from trendy full-body scans to viral "biohacking" tests—it's easy to miss the tools that are actuall...
Hormone Therapy After the FDA Warning Label Change: What Women Need to Know
There has been a dramatic change when it comes to hormone therapy. In the U.S., the FDA essentially admitted it had taken the wrong approach for decades, potentially keeping millions of women from ...
Exercise for Knee Arthritis: What the Evidence Actually Shows
Knee arthritis affects millions of people — and many are managing it with advice that research has since overturned. Understanding what the current evidence actually says about joint health, physic...
NMN and NR Supplements: What the Human Evidence Actually Shows
Over the last decade, NMN and NAD+ supplements were hyped as groundbreaking tools in the fight against aging. Boost your NAD+ levels, the story went, and you might slow aging, boost energy, and eve...
Zinc Supplement Guide: Forms, Dosing, Benefits and Safety
Table of Contents Overview Forms and Bioavailability Evidence for Benefits Recommended Dosing Safety and Side Effects Drug Interactions Dietary Sources References Overview Zinc is an essential tr...
Shingles Vaccine and Dementia Risk: What the Research Now Shows
Something remarkable has emerged from a completely unexpected corner of medicine. Medicine is full of examples where there's been failure after failure to treat a specific health condition, only fo...
Weight Loss Supplements: Evidence-Based Guide to Efficacy and Safety
Overview More than two-thirds of adults and nearly one-third of children and adolescents in the United States are overweight or have obesity [1][2]. Approximately 45% of Americans who are overweigh...
Coffee and Heart Health: What the Research Actually Shows
There was absolute panic in 1981. Imagine sitting at the table, enjoying a morning cup of coffee, with the day's paper spread out in front of you. Your eyes fall on a headline in bold, black letter...
Retatrutide Phase 3 Trial: 28.7% Weight Loss Compared to Tirzepatide
A phase 3 clinical trial has demonstrated 28.7% weight loss over 68 weeks with a new drug called retatrutide. The trial also showed substantial relief from knee osteoarthritis pain — an unexpected ...
PCSK9 Inhibitors: How Gene-Guided Therapy Is Transforming Heart Disease Prevention
A revolutionary approach to cholesterol-lowering has changed the landscape of cardiovascular medicine. For decades, LDL cholesterol has been recognised as a central driver of heart disease. But rec...
Vitamin K2 Benefits, Forms, Dosing, and Drug Interactions
Vitamin K is a group of fat-soluble vitamins sharing a common 2-methyl-1,4-naphthoquinone ring structure, essential for blood clotting, bone metabolism, and cardiovascular health. The designation "...
Exercise Snacks: The Science Behind Short Bursts of Movement
There is one insight that consistently changes the direction of a patient's health—and it has nothing to do with joining a gym. You don't need a gym membership to improve fitness or protect the hea...
Omega-3 Fish Oil and Heart Health: What the Evidence Shows
Table of Contents Early Promise, Followed by Disappointments A New Breakthrough in High-Risk Patients What This Means for the Rest of Us References Omega-3 research has had its share of failures...
Vitamin E: Forms, Evidence, and Safety — A Research Guide
Vitamin E is not a single molecule but a family of eight fat-soluble compounds with antioxidant activity: four tocopherols (alpha, beta, gamma, delta) and four tocotrienols (alpha, beta, gamma, del...
What the TARGET-D Trial Reveals About Vitamin D and Heart Health
A new vitamin D trial has raised important questions about the advice clinicians give — and the approach many have taken to vitamin D testing and supplementation. Because it takes a novel approach,...
Blood Pressure Targets: What the Evidence Actually Says
Is something significant happening right under our noses? There is a change that has quietly crept up over the past few decades — so gradual that most people have barely noticed. Since the 1970s, d...
Normal BMI, Hidden Heart Risk: What Waist Circumference Reveals
Many people feel reassured when their BMI falls in the normal range. The scale shows a healthy number, the ratio of weight to height looks right — and at a time when obesity rates are high, a norma...
Vitamin C Supplements: Evidence-Based Guide to Benefits, Forms, and Dosing
Table of Contents Overview Forms and Bioavailability Evidence for Health Benefits Recommended Dosing Dietary Sources Safety and Side Effects Drug Interactions References 1. Overview Vitamin C (L-...