Does Ezetimibe Work? What the Evidence Shows
Category: Preventative Care
The FDA-Approved Alzheimer's Blood Test: What It Can and Cannot Tell You
The results hit like a ton of bricks — and they have critical implications for the recently FDA-approved Alzheimer's blood test. Researchers were packed wall-to-wall at a conference in San Diego. T...
Testosterone, Castration, and Lifespan: What the Research Shows
A massive new study published in Nature found that castration increases lifespan across vertebrate species, including zoo mammals, rodents, and wild animals [1]. This aligns with historical human d...
2026 Dietary Guidelines: What the Science Actually Says
For years, the message has been to "eat real food." It sounds simple, but the real challenge is figuring out what that actually means—and how official guidelines define it. With the release of the ...
Evidence-Based Cancer Screening: Which Tests Actually Save Lives
When it comes to preventing cancer, early detection is everything. But with all the noise online—from trendy full-body scans to viral "biohacking" tests—it's easy to miss the tools that are actuall...
Hormone Therapy After the FDA Warning Label Change: What Women Need to Know
There has been a dramatic change when it comes to hormone therapy. In the U.S., the FDA essentially admitted it had taken the wrong approach for decades, potentially keeping millions of women from ...
Exercise for Knee Arthritis: What the Evidence Actually Shows
Knee arthritis affects millions of people — and many are managing it with advice that research has since overturned. Understanding what the current evidence actually says about joint health, physic...
NMN and NR Supplements: What the Human Evidence Actually Shows
Over the last decade, NMN and NAD+ supplements were hyped as groundbreaking tools in the fight against aging. Boost your NAD+ levels, the story went, and you might slow aging, boost energy, and eve...
Shingles Vaccine and Dementia Risk: What the Research Now Shows
Something remarkable has emerged from a completely unexpected corner of medicine. Medicine is full of examples where there's been failure after failure to treat a specific health condition, only fo...
Coffee and Heart Health: What the Research Actually Shows
There was absolute panic in 1981. Imagine sitting at the table, enjoying a morning cup of coffee, with the day's paper spread out in front of you. Your eyes fall on a headline in bold, black letter...
Retatrutide Phase 3 Trial: 28.7% Weight Loss Compared to Tirzepatide
A phase 3 clinical trial has demonstrated 28.7% weight loss over 68 weeks with a new drug called retatrutide. The trial also showed substantial relief from knee osteoarthritis pain — an unexpected ...
PCSK9 Inhibitors: How Gene-Guided Therapy Is Transforming Heart Disease Prevention
A revolutionary approach to cholesterol-lowering has changed the landscape of cardiovascular medicine. For decades, LDL cholesterol has been recognised as a central driver of heart disease. But rec...
Omega-3 Fish Oil and Heart Health: What the Evidence Shows
Table of Contents Early Promise, Followed by Disappointments A New Breakthrough in High-Risk Patients What This Means for the Rest of Us References Omega-3 research has had its share of failures...
What the TARGET-D Trial Reveals About Vitamin D and Heart Health
A new vitamin D trial has raised important questions about the advice clinicians give — and the approach many have taken to vitamin D testing and supplementation. Because it takes a novel approach,...
Blood Pressure Targets: What the Evidence Actually Says
Is something significant happening right under our noses? There is a change that has quietly crept up over the past few decades — so gradual that most people have barely noticed. Since the 1970s, d...
Normal BMI, Hidden Heart Risk: What Waist Circumference Reveals
Many people feel reassured when their BMI falls in the normal range. The scale shows a healthy number, the ratio of weight to height looks right — and at a time when obesity rates are high, a norma...
Melatonin and Heart Failure: What the 89% Headline Gets Wrong
People who use melatonin supplements have an 89% higher risk of developing heart failure, according to a new study of over 130,000 adults [1]. And there were two other equally grim findings covered...
IV Therapy Clinics: The Risks, Costs, and Lack of Evidence
It's a nearly $3 billion market and growing fast. IV therapy clinics—where you can get cocktails of vitamins and other nutrients dripped directly into your veins—are supposed to do everything from ...
Cholesterol and Dementia Risk: What a 1-Million-Person Study Reveals
A study of over 1 million people has found impressive dementia risk reductions linked to cholesterol management — offering some of the strongest evidence yet on how long-term LDL lowering affects b...
Fatty Liver Disease: GLP-1 Medications, Diet, and Lifestyle Treatment Guide
GLP-1 medications have emerged as a significant advance in treating fatty liver disease — the FDA approved semaglutide (Wegovy) for this indication in 2024. But which GLP-1 is most effective? How s...
Polypharmacy and Deprescribing: When Medications Do More Harm Than Good
Over 40% of adults over 75 are prescribed 5 or more medications [1]. While those medications may have been appropriate at prescription, the risk–benefit balance shifts as the body ages—and drugs th...
GLP-1 Microdosing for Healthy Adults: What the Evidence Actually Shows
Tech entrepreneur Bryan Johnson stirred up considerable interest when he began a microdosing experiment in late 2024 [1]. His experiment had some unexpected results — as we'll see in a moment. And...
Sleep Apnea and Brain Aging: What the Research Reveals
Every night, millions of people fall asleep—and without realising it—they stop breathing. Not just once, but over and over again. This isn't simply a matter of snoring. It's a serious medical condi...
Low-Dose Lithium and Cognitive Health: What the Research Shows
"Lithium deficiency is … a potential common mechanism for the … degeneration of the brain that leads to the onset of Alzheimer's disease." That's the conclusion from a groundbreaking study publishe...
Potassium Deficiency and Stroke Risk: What the Research Shows
Strokes are one of the leading causes of death globally [1]. Yet one of the most significant—and most overlooked—stroke risk factors is surprisingly easy to address. Research consistently points to...