LDL, ApoB and Heart Attack Risk: What the Evidence Shows
Category: Research
Early-Onset Colon Cancer: Three Research Teams, Three Suspects
Colon cancer rates in people under 50 have roughly doubled in twenty years. Nobody knows why. The incidence in the sigmoid colon nearly doubled from 1998 to 2022 in people aged 20–49, and 22% of al...
Aspirin and Cancer Prevention: What the Latest Evidence Shows
In 2010, an Oxford neurologist named Peter Rothwell published a paper in The Lancet that rewrote medical guidelines around the world. After analyzing eight randomized trials and twenty-five thousan...
Statins and Cholesterol: Separating Side-Effect Myths from the Evidence
Fifty-five years ago, a Japanese biochemist by the name of Akira Endo isolated a compound from a mold growing on rice in a Kyoto grain shop. It would go on to prevent more heart attacks than almost...
Heart Attack Risk Factors: What Research on 9 Million People Reveals
On July 20, 1984, Jim Fixx — the man whose bestselling book on running had inspired millions of Americans to get in shape — dropped dead of a massive heart attack during his daily run on a quiet Ve...
GLP-1 and Cartilage Regeneration: What the 2026 Semaglutide Study Found
In the early 1990s, an endocrinologist named John Eng walked into his lab at a VA hospital in the Bronx with a vial of dried Gila monster venom. He'd ordered it from a mail-order catalog from a ser...
The LDL Cholesterol Target the Evidence Actually Supports
In 2006, researchers in Dallas found a woman who broke everything science thought it knew about cholesterol. She was 32 years old. A healthy aerobics instructor. Normal liver, normal kidneys, no h...
Cold Remedies That Actually Work: Zinc Lozenges, Saline Rinse, and Honey
In 1979, a 3-year-old girl named Karen was undergoing chemotherapy for leukemia in Austin, Texas. The treatment was saving her life — but it had destroyed her immune system. Every cold hit her hard...
The Anti-Aging Supplement Scam: What the ITP's 20-Year Record Actually Shows
In 2023, the most rigorous lifespan-testing program in the world published its most exciting result in 14 years. A supplement available at any pharmacy — astaxanthin — had extended male mouse lifes...
NMN and NR Supplements: What the Evidence Actually Shows About NAD Precursors
Charles Brenner is not a scammer. He's a genuine biochemist — the man who discovered nicotinamide riboside back in 2004. He's published hundreds of papers. And when a new study came out showing tha...
Full-Body MRI Scans: What the Evidence Says Before You Book One
Table of Contents The Promise The Controversy What the Evidence Shows References A booming industry is selling full-body MRI scans directly to the public — no doctor referral required. Celebriti...
Sodium and Blood Pressure: What the Research Actually Shows
In 1942, a 33-year-old woman walked into a hospital with a blood pressure so high, it was destroying her eyes. Her kidneys were failing. At the time, there were no effective treatments. So in a las...
Diet Quality Beats Low Fat vs Low Carb: Evidence from 5.2 Million Person-Years
A study that tracked 5,248,916 person-years of follow-up has confirmed what the best diet for heart health actually looks like — and the answer may upend decades of nutrition debate [1]. The nutrit...
Oral Hyaluronic Acid Supplements: What the Research Actually Shows
Here is the exact moment where the hyaluronic acid story looks like it comes crashing down. A ground-breaking 2023 study radioactively labeled the hyaluronic acid in supplements to see if it is abs...
Nitric Oxide: Why Arugula Outperforms Supplements
Nitric oxide levels fall with age — and this decline is linked to an array of age-related problems in areas like heart, brain, reproductive, and muscle health [1][2]. Nitric oxide acts as a critica...
Melatonin and Heart Health: What 63 Randomized Trials Actually Show
Contrasting headlines have left melatonin users confused. One alarming 2025 study linked melatonin use to a sharp increase in heart failure risk [1]. Then a separate study told a completely differe...
High-Volume Exercise and Arterial Plaque: What the Evidence Really Shows
A study just published reveals a startling relationship that's the opposite of what most assume. It found that the most heavily trained athletes were almost six times more likely to have plaque in ...
Skin Aging: Evidence-Based Guide to Diet, Exercise, Sleep, Sunscreen, and Retinoids
Here are the most evidence-backed, affordable strategies to reduce the signs of skin aging — based on the latest human clinical research. The good news: most of them cost nothing at all. Table of ...
Coffee and Dementia Risk: What a 131,821-Person Study Found
Right now, more than 7 million Americans are living with Alzheimer's disease. By 2060, that number is projected to nearly double to 13.8 million people. Between 2000 and 2022, deaths from Alzheimer...
Microneedling for Skin: Clinical Evidence, Results, and At-Home Device Risks
Microneedling has been exploding in popularity. It's claimed to reduce scars, wrinkles, and more. But it sounds a bit counterintuitive: improving skin and treating the signs of aging by sticking a ...
Nitric Oxide Supplements: What the Research Actually Shows
Nitric oxide supplement research is more promising than many people expect—but the gap between clinical evidence and what supplement companies actually deliver is striking. This article breaks down...
Saturated Fat and Heart Disease: What the Evidence Actually Shows
Is saturated fat a problem for our hearts, or not? It's a controversy people have been arguing over for decades. Voices on both sides of the question are easy to find. The debate got a fresh jolt o...
Early-Onset Cancer Risk: What the Data Shows and How to Respond
Cancer rates appear to be skyrocketing in people under 50 [1][2]. Gen X, Millennials, and even Gen Z are being diagnosed at significantly higher rates than previous generations were at the same a...
Taurine Supplements: Evidence from 34 RCTs and 1,394 People
There was absolute despair in the supplement community a few months ago. A study on taurine appeared to smash the hopes that taurine supplements could extend lifespan. The controversy never quite j...
Turmeric & Curcumin Supplements: What the Research Actually Shows
Lies and deception characterise the majority of turmeric and curcumin supplements on the market today. That's a strong claim — but the evidence backs it up. There are legitimate use-cases for curcu...