How to Reduce Visceral Fat: An Evidence-Based Guide
Does Ezetimibe Work? What the Evidence Shows
In August 1990, a chemist named Duane Burnett walked into John Clader's office in New Jersey to discuss the results of their failed experiment. Together, they had spent months building molecules to...
BPC-157: Does It Work, and Did It Just Get FDA Approval?
BPC-157 is one of the most talked-about peptides on the internet. Athletes inject it for tendon and joint injuries, podcast guests credit it with fixing pain that nothing else could touch, and in J...
Jeremy Clarkson Says Lie to Your Doctor — Do Cancer Screens Save Lives?
When Jeremy Clarkson went public about surviving prostate cancer, he offered some blunt advice: if your doctor won't test you, lie to get the test. The clip spread quickly — and it raised a questio...
What Is a Normal Blood Pressure? Finding the Right Target for You
What is a normal blood pressure — and what should you actually be aiming for? The honest answer is that there is no single healthy blood pressure target that fits everyone. The right number depends...
Epicardial Fat: How to Reduce the Fat Around Your Heart
There's a type of fat that sits in direct contact with the heart. Because there's no barrier between it and the heart, it pumps inflammatory molecules — things like interleukin-6 and TNF-alpha — st...
Antioxidant Supplements: When High Doses Help and When They Harm
Earlier this month, one of the most rigorous trials ever run on a vitamin was stopped early — because the people getting the vitamin were dying faster than the people getting nothing [1]. It was vi...
Vitamin K2 and Coronary Calcium: Does It Protect Your Heart?
A year ago, the heart evidence for vitamin K2 looked intriguing but unproven — the field was waiting on a bigger, cleaner trial before anyone got excited. That trial has now landed, and it did exac...
Do Anti-Aging Supplements Actually Work? The Fisetin Evidence
There's a man in Wales who earns millions of dollars by reading other people's research. He sits down with papers that have already passed peer review, already been printed in the biggest journals ...
Bemotrizinol: The New Anti-Aging Sunscreen Filter the FDA Just Approved
Walk into a pharmacy in Europe, Japan, or Australia and you’ll find a sunscreen ingredient that protects skin from the signs of aging better than almost anything sold in the United States — without...
Muscle Loss on GLP-1 Drugs: What the Evidence Actually Shows
In 2004, a baby was born in Germany who was, by any normal measure, impossible. He was a few days old, and he already had visible muscles — his thighs and upper arms looked like a tiny bodybuilder....
The Undruggable Gene: How Daraxonrasib Doubled Survival in Pancreatic Cancer
A room full of cancer doctors rose to their feet at the 2026 American Society of Clinical Oncology (ASCO) conference, applauding the full results of a new cancer trial [1][2] — one with the potenti...
PCSK9 Gene Editing and LDL Cholesterol: How VERVE-102 Works
In April 2024, the trial that was supposed to end heart disease at the source nearly ended in disaster. One of the initial patients to receive the world's first gene-editing infusion designed to p...
Microplastics Research: Why the Headlines Are Wrong (and What Actually Matters)
Madeline Clough, a grad student at the University of Michigan, stumbled upon something that would turn out to be quite embarrassing for the microplastics research field. The popular claim is that ...
Low-Dose Tirzepatide (Zepbound): Evidence Beyond Weight Loss
Tirzepatide — the active ingredient in Mounjaro and Zepbound — was designed as a blood-sugar drug. But across a sequence of large randomised trials, it and its GLP-1 cousins have kept producing ben...
Omega-3 and Brain Health: What a 2026 Alzheimer's Study Got Wrong
Table of Contents The Study Landed What The Study Didn't Measure — The Bottle What The Study Didn't Measure — The Co-Factor What The Evidence Suggests References In 2024, a video titled Your Bra...
Shingles Vaccine and Cardiovascular Health: What the Research Shows
In 2023, a Stanford researcher named Pascal Geldsetzer was examining the way Wales had rolled out the shingles vaccine a decade earlier — and noticed something peculiar. To ration the limited supp...
Seed Oils and Health: What the Evidence Actually Shows
The internet is awash with videos and articles warning about the dangers of seed oils — that they're toxic, inflammatory, and terrible for human health. This article examines where these concerns c...
Early-Onset Colon Cancer: Three Research Teams, Three Suspects
Colon cancer rates in people under 50 have roughly doubled in twenty years. Nobody knows why. The incidence in the sigmoid colon nearly doubled from 1998 to 2022 in people aged 20–49, and 22% of al...
Aspirin and Cancer Prevention: What the Latest Evidence Shows
In 2010, an Oxford neurologist named Peter Rothwell published a paper in The Lancet that rewrote medical guidelines around the world. After analyzing eight randomized trials and twenty-five thousan...
Statins and Cholesterol: Separating Side-Effect Myths from the Evidence
Fifty-five years ago, a Japanese biochemist by the name of Akira Endo isolated a compound from a mold growing on rice in a Kyoto grain shop. It would go on to prevent more heart attacks than almost...
Heart Attack Risk Factors: What Research on 9 Million People Reveals
On July 20, 1984, Jim Fixx — the man whose bestselling book on running had inspired millions of Americans to get in shape — dropped dead of a massive heart attack during his daily run on a quiet Ve...
GLP-1 and Cartilage Regeneration: What the 2026 Semaglutide Study Found
In the early 1990s, an endocrinologist named John Eng walked into his lab at a VA hospital in the Bronx with a vial of dried Gila monster venom. He'd ordered it from a mail-order catalog from a ser...
The LDL Cholesterol Target the Evidence Actually Supports
In 2006, researchers in Dallas found a woman who broke everything science thought it knew about cholesterol. She was 32 years old. A healthy aerobics instructor. Normal liver, normal kidneys, no h...
Cold Remedies That Actually Work: Zinc Lozenges, Saline Rinse, and Honey
In 1979, a 3-year-old girl named Karen was undergoing chemotherapy for leukemia in Austin, Texas. The treatment was saving her life — but it had destroyed her immune system. Every cold hit her hard...