BPC-157: Does It Work, and Did It Just Get FDA Approval?
Category: Supplements
Saw Palmetto & Prostate Supplements: Evidence Review of Benefits, Forms, and Dosing
Saw palmetto (Serenoa repens) is a small palm tree native to the southeastern United States and West Indies, growing up to 10 feet tall with fan-shaped leaves [1][2]. The plant's primary medicinal ...
Probiotics: Evidence-Based Guide to Strains, Dosing and Safety
Table of Contents Overview Forms and Delivery Evidence for Health Benefits Recommended Dosing Safety and Side Effects Drug Interactions Dietary Sources References Overview Probiotics are live mic...
Evidence-Based Supplements: Omega-3, Multivitamin, and Sleep
Not every supplement is worth taking. A family medicine doctor with a research background narrowed the list down to three — and the reasoning is grounded in clinical trial data, not marketing. This...
Longevity Clinics Are Over-Testing You — What the Evidence Shows
There's an engineering concept that applies directly to medicine: "the best part is no part. The best process is no process." In clinical practice, sometimes the best test is no test, and the best ...
Prebiotics: Types, Benefits, Dosing, and Side Effects
Prebiotics are non-digestible carbohydrates — primarily complex sugars and fibers — that pass through the upper gastrointestinal tract undigested and serve as fermentable substrates ("food") for be...
PQQ (Pyrroloquinoline Quinone): Science-Based Guide to Benefits, Dosing, and Safety
Pyrroloquinoline quinone (PQQ) is a redox-active, water-soluble quinone compound with the chemical structure 4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid [1][2]. It is ...
Resistance Training and Aging: How Exercise Preserves Muscle Function
A world-renowned researcher, Dr. Brad Schoenfeld, recently highlighted a study he described as "the closest thing we have to the fountain of youth" [1]. This article explores that study and Dr. Sc...
Colchicine and Heart Disease: How Inflammation Drives Cardiovascular Risk
A new study published in the European Heart Journal found that a cheap anti-inflammatory drug cuts heart disease risk by 12%. The finding highlights something many people overlook: inflammation is ...
GLP-1 and SGLT2 Inhibitors: What the Evidence Shows on Dementia Risk
GLP-1 agonists like Ozempic were a turning point in the management of type 2 diabetes. Combined with SGLT2 inhibitors—a second class of diabetes medication—these treatments transformed outcomes for...
Potassium: Benefits, Forms, Dosing, and Safety Guide
Potassium is an essential mineral and the most abundant intracellular cation in the human body. It is required for normal cell function because of its role in maintaining intracellular fluid volume...
Taurine Supplements and Aging: What Two New Studies Reveal
Two years ago, a breakthrough study yielded exciting evidence that taurine could help combat aging. But a study published since then casts serious doubt on those earlier results. And this is actual...
Pomegranate Juice and Supplements: Evidence-Based Benefits, Dosing, and Safety
Table of Contents Overview Forms and Bioavailability Evidence for Benefits Recommended Dosing Safety and Side Effects Drug Interactions Dietary Sources References Overview Pomegranate (Punica g...
Bone Loss After 40: How to Protect Bone Density with Exercise and Nutrition
One in three people who break their hip will be dead within 1 year. After 10 years, only 8.5% will be alive, compared to 39.8% in the general population [1]. Those numbers reflect a broader pattern...
Magnesium Dose & Forms: Evidence-Based Guide to Absorption, Deficiency, and Supplementation
Table of Contents Magnesium's Role in the Body Mistake #1: Not Getting Enough Magnesium and Health Conditions Mistake #2: How We Assess Magnesium How to Reach Your Recommended Magnesium Intake Cho...
Lowering Blood Pressure: Why the 120 Target Cuts Heart Risk by 21%
Table of Contents The new study The revision At-home BP measurement Reducing high BP Reference list The new study A new study reinforces why the medical approach to lowering heart attack risk i...
Phosphatidylserine: Evidence-Based Guide to Benefits, Forms, and Dosing
Phosphatidylserine (PS) is a phospholipid that forms a critical structural component of cell membranes throughout the body, with particularly high concentrations in the brain. Research interest beg...
Omega-3 (EPA & DHA): Evidence-Based Guide to Benefits, Forms, and Dosing
1. Overview Omega-3 fatty acids are a family of polyunsaturated fatty acids (PUFAs) characterized by a carbon-carbon double bond located three carbons from the methyl end of the fatty acid chain. T...
Olive Leaf Extract: Evidence-Based Guide to Benefits, Dosing, and Safety
Olive leaf extract (OLE) is derived from the leaves of the olive tree (Olea europaea), an evergreen species in the Oleaceae family native to the Mediterranean Basin. The leaves contain a rich array...
Vitamin D Dosing for Immune Health: What the Research Actually Shows
There's been so much hype around vitamin D—and, unfortunately, most studies have been disappointing when it comes to real-world benefits. But a brand-new study points to a place where vitamin D see...
Collagen Peptides for Skin: What the Evidence Shows
Collagen is simple, safe, and well-studied, and the evidence increasingly supports its ability to improve markers of skin health. A 2025 randomized controlled trial adds to this picture — and also ...
Nitric Oxide Supplements: Evidence Guide to Forms, Benefits, and Dosing
Nitric oxide (NO) is a highly reactive, short-lived gaseous free radical that functions as one of the most critical signaling molecules in human physiology. It is produced endogenously by nitric ox...
Exercise Snacks: The Science of How Little Exercise You Actually Need
Everyone knows exercise is crucial for health. But with packed schedules, the challenge is extracting the maximum benefit from whatever time is available. The good news is that emerging research is...
Nattokinase: Evidence-Based Guide to Benefits, Forms, Dosing, and Safety
Table of Contents Overview Forms and Bioavailability Evidence for Benefits Recommended Dosing Safety and Side Effects Drug Interactions Dietary Sources References Overview Nattokinase is a seri...
NMN, NR, and NADH Supplements: What the Evidence Actually Shows
Nicotinamide adenine dinucleotide (NAD) is a coenzyme essential for energy production in mitochondria throughout the body. It exists in two interconvertible forms: NAD+ (the oxidized form, carrying...