LDL, ApoB and Heart Attack Risk: What the Evidence Shows
Category: Research
Heart Disease Prevention: Saturated Fat, LDL Cholesterol, and the Diet Evidence
Across the world, cardiovascular disease death rates have been falling dramatically [1]. Today, science offers tools that could virtually eliminate coronary heart disease as a cause of death. But ...
Antioxidants and Aging: What the Research Shows
For years, antioxidants were hailed as miracle compounds that could slow aging, improve heart health, and enhance physical performance. Then, almost as quickly as they rose to fame, they fell out o...
Peanut Allergy Prevention: The Early Introduction Evidence
Dr. Ruchi Gupta did everything right to protect her daughter from peanut allergies — and it backfired. Dr. Gupta was a young doctor researching food allergies. She knew the advice. At the time, in ...
The FDA-Approved Alzheimer's Blood Test: What It Can and Cannot Tell You
The results hit like a ton of bricks — and they have critical implications for the recently FDA-approved Alzheimer's blood test. Researchers were packed wall-to-wall at a conference in San Diego. T...
Testosterone, Castration, and Lifespan: What the Research Shows
A massive new study published in Nature found that castration increases lifespan across vertebrate species, including zoo mammals, rodents, and wild animals [1]. This aligns with historical human d...
2026 Dietary Guidelines: What the Science Actually Says
For years, the message has been to "eat real food." It sounds simple, but the real challenge is figuring out what that actually means—and how official guidelines define it. With the release of the ...
Evidence-Based Cancer Screening: Which Tests Actually Save Lives
When it comes to preventing cancer, early detection is everything. But with all the noise online—from trendy full-body scans to viral "biohacking" tests—it's easy to miss the tools that are actuall...
Hormone Therapy After the FDA Warning Label Change: What Women Need to Know
There has been a dramatic change when it comes to hormone therapy. In the U.S., the FDA essentially admitted it had taken the wrong approach for decades, potentially keeping millions of women from ...
Exercise for Knee Arthritis: What the Evidence Actually Shows
Knee arthritis affects millions of people — and many are managing it with advice that research has since overturned. Understanding what the current evidence actually says about joint health, physic...
NMN and NR Supplements: What the Human Evidence Actually Shows
Over the last decade, NMN and NAD+ supplements were hyped as groundbreaking tools in the fight against aging. Boost your NAD+ levels, the story went, and you might slow aging, boost energy, and eve...
Shingles Vaccine and Dementia Risk: What the Research Now Shows
Something remarkable has emerged from a completely unexpected corner of medicine. Medicine is full of examples where there's been failure after failure to treat a specific health condition, only fo...
Coffee and Heart Health: What the Research Actually Shows
There was absolute panic in 1981. Imagine sitting at the table, enjoying a morning cup of coffee, with the day's paper spread out in front of you. Your eyes fall on a headline in bold, black letter...
Retatrutide Phase 3 Trial: 28.7% Weight Loss Compared to Tirzepatide
A phase 3 clinical trial has demonstrated 28.7% weight loss over 68 weeks with a new drug called retatrutide. The trial also showed substantial relief from knee osteoarthritis pain — an unexpected ...
PCSK9 Inhibitors: How Gene-Guided Therapy Is Transforming Heart Disease Prevention
A revolutionary approach to cholesterol-lowering has changed the landscape of cardiovascular medicine. For decades, LDL cholesterol has been recognised as a central driver of heart disease. But rec...
Omega-3 Fish Oil and Heart Health: What the Evidence Shows
Table of Contents Early Promise, Followed by Disappointments A New Breakthrough in High-Risk Patients What This Means for the Rest of Us References Omega-3 research has had its share of failures...
What the TARGET-D Trial Reveals About Vitamin D and Heart Health
A new vitamin D trial has raised important questions about the advice clinicians give — and the approach many have taken to vitamin D testing and supplementation. Because it takes a novel approach,...
Blood Pressure Targets: What the Evidence Actually Says
Is something significant happening right under our noses? There is a change that has quietly crept up over the past few decades — so gradual that most people have barely noticed. Since the 1970s, d...
Normal BMI, Hidden Heart Risk: What Waist Circumference Reveals
Many people feel reassured when their BMI falls in the normal range. The scale shows a healthy number, the ratio of weight to height looks right — and at a time when obesity rates are high, a norma...
Melatonin and Heart Failure: What the 89% Headline Gets Wrong
People who use melatonin supplements have an 89% higher risk of developing heart failure, according to a new study of over 130,000 adults [1]. And there were two other equally grim findings covered...
IV Therapy Clinics: The Risks, Costs, and Lack of Evidence
It's a nearly $3 billion market and growing fast. IV therapy clinics—where you can get cocktails of vitamins and other nutrients dripped directly into your veins—are supposed to do everything from ...
The Testosterone Decline Myth: What the Science Actually Shows
For years, researchers have observed a troubling trend: testosterone levels in men seem to be declining across generations. This hormone, crucial for male health, has been linked to energy, mood, m...
Vigorous Exercise Benefits: How Intensity Multiplies Health Outcomes
A landmark study has overturned one of the most fundamental assumptions in exercise science — and the implications reshape how anyone should structure their physical activity for maximum health ben...
Fatty Liver Disease: GLP-1 Medications, Diet, and Lifestyle Treatment Guide
GLP-1 medications have emerged as a significant advance in treating fatty liver disease — the FDA approved semaglutide (Wegovy) for this indication in 2024. But which GLP-1 is most effective? How s...
Longevity Clinics Are Over-Testing You — What the Evidence Shows
There's an engineering concept that applies directly to medicine: "the best part is no part. The best process is no process." In clinical practice, sometimes the best test is no test, and the best ...