BPC-157: Does It Work, and Did It Just Get FDA Approval?
Category: Supplements
Glycine Supplements: Sleep, Metabolic Health, and the Evidence
Glycine is an amino acid involved in dozens of bodily functions — from collagen synthesis to blood sugar regulation to nerve signalling. Clinical research has identified meaningful benefits in two ...
Ezetimibe and Statins: Evidence-Based Approach to Lowering LDL Cholesterol
Heart disease is the world's biggest killer — and it is only getting worse. [1] Research continues to confirm that safe, affordable, and highly effective strategies exist for reducing cardiovascula...
NAC (N-Acetyl Cysteine): Evidence-Based Guide to Benefits, Dosing, and Safety
N-acetyl cysteine (NAC), also known as acetylcysteine, is a synthetically modified form of the amino acid cysteine. First approved by the FDA in 1963 as a prescription antidote for acetaminophen ov...
Lower Blood Pressure, Lower Dementia Risk: What the Evidence Shows
A large new study published in Nature Medicine has found that aggressively lowering blood pressure cut dementia risk by 15% over four years — and the evidence suggests the benefit compounds substan...
5 Popular Supplements That May Damage Your Blood Vessels
Some of the most popular supplements on the market may be actively damaging blood vessels — yet millions of people take them daily without any awareness of the risk. It is not just one supplement. ...
How Morning Light Improves Sleep Quality
Table of Contents The Impact of Light on Sleep Mechanisms: How Circadian Biology Works Practical Strategies for Morning Light Reference List The Impact of Light on Sleep Small, consistent change...
Multivitamins: What the Evidence Actually Shows
Overview Multivitamin/mineral (MVM) supplements are dietary products containing combinations of essential vitamins and minerals intended to compensate for potential nutritional shortfalls in the di...
Milk Thistle (Silymarin): Evidence-Based Guide to Benefits, Forms, Dosing, and Side Effects
Milk thistle (Silybum marianum) is a thistle-like flowering herb in the Asteraceae family, native to the Mediterranean region, southern Europe, and parts of Asia and North Africa [1][2]. It has bee...
Phytoestrogen Supplements for Menopause: Evidence, Dosing, and Safety
Table of Contents Overview Forms and Bioavailability Evidence for Benefits Recommended Dosing Safety and Side Effects Drug Interactions Dietary Sources References Overview Menopause is the perm...
Collagen Peptides: Benefits, Forms, Dosing, and Side Effects
Collagen is the most abundant protein in the human body, forming the structural backbone of skin, bone, cartilage, tendons, blood vessels, and the cornea. It is uniquely rich in the amino acids gly...
Berberine Supplements: Blood Sugar, Cholesterol and Weight Loss Evidence
Berberine has been called "nature's Ozempic" and is touted for everything from fighting cancer to alleviating depression. This article separates the marketing hype from the evidence-backed benefits...
Melatonin Supplements: Evidence, Dosing, Forms, and Safety
Melatonin is a hormone produced by the pineal gland in response to darkness, serving as the body's primary circadian rhythm signal. It plays roles in sleep-wake regulation, antioxidant defense, imm...
Manuka Honey: Evidence-Based Guide to Benefits, Grading, and Dosing
Manuka honey is a monofloral honey derived primarily from the nectar of the manuka tree (Leptospermum scoparium), which grows throughout New Zealand and Eastern Australia [1]. Unlike conventional h...
Vitamin D Supplements: What the Latest Endocrine Society Guidelines Actually Say
Vitamin D has attracted enormous interest in recent years. Supporters have described it as a cure-all—capable of boosting heart health, lifespan, immune function, and more. But is it really the mag...
Creatine Supplementation: Evidence-Based Guide to Benefits, Forms, Dosage, and Safety
Creatine is a non-essential amino acid naturally produced in the human body from arginine, glycine, and methionine, primarily in the kidneys and liver. Approximately 95% of the body's creatine is s...
Mangosteen Supplements: Evidence Review of Xanthones, Dosing, and Safety
Mangosteen (Garcinia mangostana) is a tropical fruit native to Southeast Asia whose rind is rich in xanthones — a class of polyphenolic compounds with potent antioxidant and anti-inflammatory prope...
Magnesium Supplement Guide: Forms, Benefits, and Dosing
Table of Contents Overview Forms and Bioavailability Evidence for Health Benefits Recommended Dosing Dietary Sources Safety and Side Effects Drug Interactions Frequently Asked Questions References...
Creatine and Lean Mass: What a 2025 Study Actually Shows
Table of Contents The Existing View The New Study Response to the Study Creatine and Performance Back to the Study References A recent study is challenging everything researchers thought they kn...
Vitamin D3 Supplement Guide: Dosing, Forms, Benefits, and Safety
Table of Contents 1. Overview 2. Forms and Bioavailability 3. Evidence for Health Benefits 4. Recommended Dosing 5. Safety and Side Effects 6. Drug Interactions 7. Dietary Sources 8. References Re...
Maca Root: Evidence-Based Guide to Benefits, Forms, Dosing, and Safety
Overview Maca (Lepidium meyenii), also known as Peruvian ginseng, is a starchy root vegetable in the Brassicaceae (cruciferous) family, native to the high-altitude central Andes of Peru at elevatio...
Creatine Supplements: Brain Health, Muscle, and Safety — What the Research Shows
Creatine is one of the most studied supplements in sports science — but emerging research is revealing benefits that extend well beyond muscle building. Recent trials are uncovering how creatine ma...
Taurine Supplementation: What the Research Actually Shows
There's a popular ingredient in energy drinks that's recently been gaining serious attention for its potential to support healthy aging and key health parameters. Does the research support the hype...
L-Lysine Benefits, Dosing, Forms, and Side Effects: Evidence Review
Lysine (L-lysine) is one of nine essential amino acids that the human body cannot synthesize and must obtain from dietary sources [1][2]. It plays fundamental roles in protein synthesis, collagen f...
Lycopene: Evidence-Based Guide to Benefits, Forms, and Dosing
Lycopene is a fat-soluble red pigment and carotenoid antioxidant found in tomatoes, watermelon, pink grapefruit, guava, and apricots. It is one of the most potent biological antioxidants identified...